Randomized Controlled Trial

Lion’s Mane and Cognitive Function in Older Adults

Mori K, Inatomi S

Phytotherapy ResearchMarch 2009

Plain Language Summary

Lion’s Mane improved brain function in older adults but may need to be taken continuously.

Key Findings

  • 1Significant cognitive improvement
  • 2Benefits increased over time
  • 3Effects reversed after stopping

Abstract

This RCT investigated Lion’s Mane effects on cognitive function in 50-80 year olds with mild cognitive impairment.

Study Limitations

Small sample size. Benefits reversed after cessation.

Compounds Studied

Lion’s Mane and Cognitive Function in Older Adults | Natural Compare